Covid-19: Remdesivir should not be used in hospitalized patients with Covid-19, advises WHO | Zoom Fintech


Covid-19 : Remdesivir should not be used if you are hospitalized Covid-19 sick, WHO advises

Antiviral remdesivir should not be used as therapy for people in hospital Covid-19 sick, the World Well Being Group said Thursday, just one month after the Meals and Drug Administration cleared the drug to treat hospitalized patients over the age of 12. Covid-19.

Remdesivir, also called Veklury, and the steroid dexamethasone are the only drugs allowed to treat Covid-19 the sick ones. However, a huge current global research on the effectiveness of remdesivir, led by the WHO, has confirmed that remdesivir has little to no impression on people in hospital, contradicting previous trials.

“Remdesivir does not have a significant impact on mortality or on various key outcomes for people with the disease, comparable to the need for mechanical airflow or the time needed for medical reinforcement,” consultants wrote. of the WHO Guideline Improvement Group in a statement. The assessment was revealed in The BMJ, a medical journal.

In light of preliminary knowledge from the WHO ‘Solidarity’ trial – which included knowledge from more than 11,200 people in 30 countries – “remdesivir is now labeled as a drug that you should not routinely use in Covid-19 sick, ”European Society for Critical Care Medicines President Jozef Kesecioglu said in an interview with Reuters.

Gilead Sciences, which makes remdesivir, questioned the WHO’s findings. In an emailed statement, the drugmaker said, “We have confidence that doctors dealing with entry strains recognize the medical good thing about Veklury, primarily based on strong evidence from a certain number of randomized and managed searches. “

While doctors and hospitals are generally not obligated to comply with the WHO recommendation, counseling may limit the use of remdesivir.

The drug remains widely used in hospitals, however, as well as in the U.S. It is licensed or licensed for use in over 50 countries, and it was one of many drugs administered to President Donald. Asset when he looked optimistic for the coronavirus in October.

Previous research by the National Institutes of Wellness found that remdesivir reduced the length of hospital stays among people with reasonable illness by about 4 days, from 15 to 11 days.

Because remdesivir is believed to work by preventing the virus from replicating, he is more likely to have an extra impression earlier in the midst of the illness, said Dr Hugh Cassiere, pulmonologist at Northwell Well being in New York City, said informed NBC Information.

“If you happen to start remdesivir very early, you expect to get more for your money,” Cassiere said.

Dr. Ken Lyn-Kew of Nationwide Jewish Well Being in Denver agreed that it is very important to review remdesivir, but he is not as keen on using the drug for people with higher illnesses. “The information provided wouldn’t really work in inpatients,” Lyn-Kew said.

Kesecioglu mentioned that there was not enough knowledge about when remdesivir is likely to be effective or for which patients, which led to the choice to discourage its routine use in intensive care.

This means that doctors should only use remdesivir often, and not as regular therapy for Covid-19 the sick ones.

Ten months after the start of the pandemic, a debate continues to rage within the medical trade as to which drugs are most effective for hospital patients Covid-19 the sick ones.

Remdesivir has potential side effects on the kidneys, according to knowledge Gilead has shared with the European Medicines Company, which is evaluating its potential toxicity.

Individually, the FDA on Thursday issued emergency use authorization for remdesivir along with Eli Lilly’s baricitinib, a tablet used to treat rheumatoid arthritis.

In an inpatient medical trial Covid-19 combination therapy was shown to reduce recovery time within 29 days of starting medications, compared to patients who received placebo with remdesivir, the FDA said in a statement. The company mentioned that the current analysis will likely be desired to verify profit.


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